Product Name : Dipotassium Glycyrrhiziate

Synonyms :  Glycyrrhizic acid Dipotassium salt;  (3-beta,20-beta)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D- glucopyranuronosyl- alpha-D-glucopyranosiduronic acid, dipotassium salt;   

CAS #　： 68797-35-3

Items　　　　　　　   Properties

Molecular formula           C₄₂H₆₂O₁₆·2K
Molar mass                      901.12 g/mol
Appearance                      white to yellowish crystalline powder
pH                                       5-6 (1% sol.)
Assay                                 95.0% min

Description :

A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to glycyrrhetic acid, which inhibits 11 beta-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.

Application :

It is effective in treatment of peptic ulcer. It is used in brewing and for confectionery and tobacco flavorings. It is frequently used in medicines to mask the unpleasant flavours. It has been used medicinally for highly effective coughs and as a mild laxative. It promotes the ejection of mucus or exudate from the lungs, bronchi, and trachea; sometimes extended to antitussives. Glycyrrhetinic acid has corticosteroid-like structure, thus is useful as an anti-inflammatory and co-emulsifier to treat skin disorders and in cosmetics.